In order to research the seismic performance of a new type of prefabricated composite lightweight wall and its influence on the seismic performance of the frame structure, a pseudo-static test is carried out by designing and fabricating three new composite lightweight wall frame-specimens with 1:2 scale, the strength of the injection mortar of the interface bin is taken as the test parameters, the failure mode, hysteresis curve, skeleton curve, stiffness degradation, cumulative energy consumption and deformation of the assembly connection part of the structure are analyzed. The results show that: 1) The bonding of the interface mortar layer makes the frame and the lightweight wall work synergistically after loading, while the frame column and wall have the same deformation trend at the initial loading stage; 2) When the loading displacement angle increases to 1%, the interface cracks, and when the displacement angle increases to 2%, the beam, column and wall are completely disengaged; 3) In the large deformation stage when the interstory displacement angle range is 2%-4%, the lightweight wall and frame structure are damaged, but the anchor connection between the wall and the frame does not fail, the wall does not fall off, and the bearing capacity of the frame decreases slowly; 4) The influence of mortar strength on the connection performance is not obvious, and the use of M3.5 mortar grouting strength can make the composite lightweight wall have appropriate stiffness when it is connected to the frame.