With the development of concrete in the direction of high performance and high strength, C100 high-strength and large-volume concrete has been gradually applied to such key engineering fields as super high-rise buildings and long-span bridges, while C100 high-strength and large-volume concrete is rarely used in underground engineering, and the related construction technology research is limited. The comprehensive application of C100 high-strength and large-volume concrete in an underground project is taken as the research object, and the design of C100 high-strength & large-volume concrete mix proportion and construction temperature control technology are studied from the engineering construction environment. Starting from the mix proportion design, the temperature field change of C100 high-strength and large-volume concrete is analyzed through numerical simulation, and such the temperature control technologies as construction process optimization, internal cooling water cooling, sequence pouring, surface insulation, winter construction control, intelligent temperature measurement and maintenance are adopted. Under the premise of satisfying the high-strength index, the control of hydration heat temperature rise and the temperature crack caused by hydration heat rise in the construction of large-section high-strength and large-volume concrete are basically solved, the design requirements are met and the construction quality of the project is ensured.