Foundation pit engineering is crucial to the safety and economic efficiency of production process of construction products. Taking deep foundation pit support in Xiangya fifth hospital as an example, aiming at unfavorable geographical location and complex construction environment conditions,different support methods are adopted. The foundation pit with small excavation depth and wide construction site is excavated by using composite soil nailing wall support combined with two-stage slope cutting. When the excavation depth of foundation pit is large,the site is limited and there is no slope position, the excavation is carried out after the rotary excavation pile combined with the prestressed anchor cable support. The construction process of this case shows that the composite soil nailing wall, pile-anchor combined support method is safe, reliable,economic and practical in the excavation depth of 20~25 m. This paper can provide reference for similar projects.