In order to study the key technologies in the jacking construction process of composite beams across expressway, a general construction plan that can ensure construction accuracy and safety is proposed based on a single-span 60m simply supported steel-concrete composite beam project and the main difficulties of jacking construction. The plan specifically includes construction technology, correction plan, construction process and steps, etc. By rationally optimizing the jacking process during the construction process, the stress conditions of the structural components under various key working conditions during the jacking construction are analyzed in detail. The strength, stiffness and deformation problems that may occur during the jacking process of the composite beam are discussed in detail, and the corresponding calculations and analyses are carried out on the composite beams after completion. Practical application shows that the proposed overall construction plan can ensure construction safety and quality, and the performance indicators of the composite beam during the jacking process meet the requirements. The results can provide certain theoretical guidance and practical value for improving the safety, efficiency and quality of the jacking construction of composite beams across expressway.